Football fans are perhaps the most superstitious people around, and for good reasons. With only 17 games in the regular season before playoffs. every aspect of each week makes the NFL feel like a do-or-die league during the fall.

Underscoring the entire schedule is that the 2025 campaign will be the last in their longtime home of Highmark Stadium, where they began playing in 1973. As their new stadium across the street is scheduled to be ready for the 2026 season, the Bills have one final chance to chase Super Bowl glory in their farewell season to their 53-year home.

The Bills schedule is out and here is Sal Maiorana's analysis of every game as Buffalo seeks a sixth straight AFC East title.