SAN FRANCISCO, Calif. (WNEM) - The Detroit Lions are in San Francisco to take on the 49ers for Monday Night ... The game is set to begin at 8:20 p.m. and tickets are still available.

Deebo Samuel and Jauan Jennings who can make big-time plays if the Lions let them. San Francisco has registered 56 receptions of 20-or-more yards this season, which is third most in the NFL behind ...

Detroit Lions fans show grit facing logistical challenges and high costs to travel 2,400 miles to cheer for a Super Bowl berth.

The San Francisco 49ers take on the Detroit Lions on "Monday Night Football" in Week 17 of the 2024 NFL season. Showcasing her meaningful work at the San Jose Family Shelter and adoration for her ...

The Detroit ... the San Francisco 49ers in Week 17 and the Vikings to the Green Bay Packers. RELATED: How Lions win over Bears impacts NFC North Here's a look at the current NFC playoff picture ...

In the updated NFC playoff picture following Sunday of Week 15, San Fransisco is still on the outside looking in. Thursday's loss made every future 49ers ... the Lions and Dolphins. While Detroit ...

San Francisco 49ers QB Brock Purdy threw a dart to WR Ricky Pearsall for a touchdown during "MNF" against the Detroit Lions. Watch highlights of San Francisco 49ers 2025 Pro Bowlers TE George ...

The Detroit Lions ... in franchise history. The Lions' offense was good and a defense that has been battered by injuries had a hard time slowing the San Francisco 49ers down, though it came ...

This week's Monday Night Football game between the Detroit Lions and the San Francisco 49ers won't have playoff implications for either team, whose post-season fates have already been determined.