The adaptors activate other relay proteins inside the cell, and this chain of protein-protein interactions creates a signal transduction pathway that ... factors (such as NF-kB and IRFs) that ...
Recent work has shown us that G3BP nucleation of stress granules in the absence of virus infection activates PKR, resulting in phosphorylation of eIF2alpha and activation of NF-kB and JNK signal ...
It also lowered the liver's production of new fats by preventing the activation of a key adverse metabolic pathway ...
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