Chronic brain inflammation can impact mood, cognition, and memory. Learn about some simple lifestyle changes that can help ...

A primary function of the TNF superfamily molecules is to regulate cell survival. In addition, signals from OX40, 4-1BB, CD27 and DR3 also synergize with T-cell receptor (TCR) signals to allow ...

Tumour Necrosis Factor TNF is crucial for defence but can drive chronic inflammation linked to arthritis and autoimmune diseases when overproduced ...

These cells produced large amounts of a protein called tumour necrosis factor (TNF), which is an important regulator of inflammation and also promotes sleep. To confirm that these cells were linked to ...

The California biotech has drawn partnerships with Eli Lilly and J&J on the promise of its approach to rebalancing the immune ...

The TNF inhibitors cause their primary effect by blocking the interaction of TNF with cell surface receptors. Biologic anti-TNF, often used in combination with MTX, is now the first choice of ...

For the first time, clinicians and scientists used a technology called "single-cell RNA-sequencing" to characterize gut samples collected before and after anti-TNF treatment, one cell at a time ...

For instance, studies have shown that astronauts frequently develop insulin resistance, a condition where the body’s cells ...