Results provide a mechanistic explanation of why early loss of p53 signaling is frequently observed in UC-associated ...

Researchers in the lab of Michael Sigal at the Max Delbrück Center and Charité—Universitätsmedizin Berlin have elucidated the role of the p53 gene in ulcerative colitis. The study ...

More than 140,000 articles have been published on molecules that mediate the intrinsic and extrinsic apoptotic cascades, such as BCL-2, TNF, NF-κB and p53. This interest in part stems from the ...