To confirm the TLR-activating adjuvants affecting peptides presented on MHC molecules specifically through TLR binding, we have used CRISPR-cas9 to knock out TLR4 and TLR9 of A20 cells and repeated ...

This study aims at describing the clinical phenotypes and disease course of patients with A20 haploinsufficiency (HA20 ... minimal inflammatory cell infiltrate, and extensive deposition of complement ...

We also chose another H-2 d cell J774A.1, a macrophage cell line, for immunopeptidome in this study. Unfortunately, MHC-II molecular expression on J774A.1 was much lower than that on A20 cells. Even 5 ...

NetApp® , the intelligent data infrastructure company, today announced updates to its portfolio of enterprise storage offerings including new NetApp AFF A-Series and AFF C-Series systems with ...

The protein factories of our cells are much more diverse than we thought they were. Scientists have now shown that cancer cells can use these so-called ribosomes to boost their invisibility cloak ...

On the Origin of Life: How the First Cell Membranes Came to Exist Nov. 13, 2024 — Few questions have captivated humankind more than the origin of life on Earth. How did the first living cells ...

A biker has been seriously injured after a collision with a car on the A20. The air ambulance was called to the scene in Ashford Road, Lenham, near Maidstone shortly before 5pm today. An air ...

Pictures from the scene of a crash that took the lives of a pregnant woman and her unborn child show the carnage left behind. The collision, which involved a police car, happened in Kidbrooke ...

But far less is known about how cells and molecules stand up to the squeezing, crushing weight of thousands of feet of seawater. “The animals that live down in the deep sea are not ones that ...

London's Air Ambulance has been flown to the scene of a crash involving a police car and another vehicle in Blackheath. The incident occurred on the A20 Eltham Road near to the junction with ...