The results showed that cordycepin significantly inhibited growth factor signaling in multiple cell lines, particularly ...

Kura Oncology (KURA) reported preclinical data supporting the development of the Company’s menin inhibitor, ziftomenib, for the treatment ...

effectively silencing both the ERK and AKT/mTOR signaling pathways and driving robust cell cycle arrest and apoptosis. Given that imatinib is well established as the frontline standard of care in ...

Combination of ziftomenib and imatinib shows robust and durable antitumor activity in imatinib-sensitive (1L) and imatinib-resistant (2L/3L) GIST models – – Proof-of-concept study of ziftomenib plus ...

THRAP3, STMN1, and GNA13—are overrepresented in blood cancers like acute myeloid leukemia (AML) and could prove to be novel ...

Rapid-Lift Advanced Neck Serum is a beauty product from a trusted manufacturer that was specifically formulated to have a ...

We expect the nemolizumab, which targets IL-31 signaling involved in pruritus ... leading to constant activation of the PI3K, AKT, mTOR or PAM pathway promoting cancer cell proliferation and ...

We are also researching genetic and molecular markers for targeted treatment of LABC in New York women with the goal of translating the Akt/mTOR pathway to treatment ... We investigate hormone ...

AKT signaling pathway is one of the most critical and extensively investigated signaling pathways. It is the central ...

A central question in adult stem cell biology is elucidating the signaling pathways regulating their dynamics and function in diverse physiological and age-related contexts. Muscle stem cells in ...