These findings highlight midlife as a critical point for healthy brain aging and provide new insights into the molecular ...

Thomas Hurd, associate professor in the Department of Molecular Genetics at the University of Toronto, will talk about mtDNA degradation at 12:55 p.m. Wednesday in Bell Engineering 2267.

Breakthrough polymer-based therapy shows promise in reversing Huntington's disease symptoms by preventing toxic protein ...

But mitochondria don’t stop at making energy; they’re also essential in triggering cell death, an essential function that, ...

A report published in PLoS Biology provides evidence that PTEN-induced putative kinase 1 (PINK1) is involved in selective autophagy of dysfunctional mitochondria. Recessive mutations in the PINK1 ...

The transferred mitochondria trigger the cell to destroy its low-performing mitochondria through autophagy—a kind of cellular ...

including the replacement of old and defective organelles such as mitochondria. Autophagy is also induced by the formation and collection of mis-folded proteins in the ER, which causes ER-stress ...

A recent study suggests that when good mitochondria go bad, the activation of both glycolysis and autophagy may permit cellular survival. In most schools, students tend to stratify into groups ...