There are two main approaches for therapy based on targeting TNF–TNF receptor (TNFR) interactions: one is to block their interactions to reduce pathogenic immune responses in autoimmune and ...
Sino Biological offers a comprehensive selection of recombinant TNF and TNFR proteins and corresponding antibodies that support drug discovery and development research on TNFs/TNFRs. TNFRSF ...
Central to this process is the interaction of FADD and procaspase-8. [58] During TNFR-1-induced apoptosis, FADD interacts with procaspase-8 via DED motifs that are present in both proteins.
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