As many as 600 people were held in a hospital overnight, the mayor of the city of Jenin told a Palestinian news agency. The death toll from the two-day operation rose to 10, officials said.

In the days since a fragile ceasefire took hold in the Gaza Strip, Israel has launched a major military operation in the occupied West Bank and suspected Jewish settlers have rampaged through two Palestinian towns.

The action came a day after President Donald Trump said he will lift sanctions on ultranationalist Israeli settlers who attacked Palestinian villages.

The announcement came shortly after President Trump rescinded Biden-era sanctions on Israeli settlers and Jewish extremists raided Palestinian villages in protest against the cease-fire in Gaza.

Prime Minister Benjamin Netanyahu said the assault on Jenin would be “extensive and significant,” as the military erected new checkpoints across the West Bank.

The Israeli military killed at least seven Palestinians in the occupied West Bank on Tuesday as the prime minister announced the start of a “large-scale military operation” in the restive city of Jenin.

Gunfire and explosions rocked the occupied West Bank's Jenin area on Wednesday, a Palestinian official and an AFP reporter said, as the Israeli military pressed on for a second day with a large-scale raid.

Jewish extremists burned buildings and vehicles in raids on Palestinian villages in the West Bank late Monday, Palestinian officials and the Israeli military said.

Israeli security forces backed by helicopters raided the volatile West Bank city of Jenin on Tuesday, killing at least eight Palestinians in what Prime Minister Benjamin Netanyahu called a "large-scale and significant military operation.