Likewise, the strength of the bond between the antibody and epitope can vary, as can the number of antibodies that bind near one another. To answer these questions in the new study, Hangartner's ...

By designing epitope-specific antibodies that precisely bind to key regions, AI offers potential breakthroughs for diseases where conventional approaches have fallen short – increasing the ...

Representative image of immunofluorescence in RAW264.7 cells expressing mCherry-TOSI treated incubated with 2μg/mL of r-mS100A9 or r-hS100A9. (CREDIT: University of Geneva (UNIGE)) ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Neoantigen vaccine is a promising breakthrough ...

Similar to the VEGF setup, gRNAs were transfected in MSOD-B cells together with a pU6-(BbsI)_CBh-Cas9-T2A-mCherry plasmid to ensure transfection efficiency and single cell sorting of positive clones.

Given the variety of microorganisms that can cause endocarditis, a multi-epitope vaccine targeting many important pathogens could be especially beneficial. Consequently, a multi-epitope vaccine was ...

This B cell epitope-based therapeutic vaccine may provide a novel immunotherapeutic agent against chronic HBV infection in humans. Achievement of hepatitis B virus surface antigen (HBsAg) loss is an ...

This study reports that activation of TFEB promotes lysosomal exocytosis and clearance of cholesterol from lysosomes, the strength of evidence for which is convincing with appropriate and validated ...

The Drosophila Gateway™ Vector collection is a set of 68 Gateway-based vectors designed to express epitope-tagged proteins in Drosophila culture cells or flies. At its core is Invitrogen's Gateway™ ...