The 49ers have ruled out two key starters versus the Cardinals in the regular season finale. Deebo Samuel and Deommodore Lenoir will not be available for them. Their 2024 season is over with.

San Francisco 49ers quarterback Brock Purdy's season is likely over, but he was able to avoid a serious injury in Monday's loss to the Detroit Lions. Head coach Kyle Shanahan told reporters on ...

No one has a clearer vision of where the 49ers stand than George Kittle. He might be the smartest player on the team -- he articulates football better than the head coach. And he's a tight end ...

The San Francisco 49ers suspended linebacker De’Vondre Campbell on Monday after he refused to enter Thursday night’s game against the Los Angeles Rams. The 49ers lost the game 12-6.

The San Francisco 49ers suffered a heartbreaking 40-34 defeat to the Detroit Lions in their Week 17 matchup on "Monday Night Football." Despite being eliminated from playoff contention ...

The 49ers’ biggest need heading into the 2025 season is the same need they had going into 2024’s start or the NFL trade deadline: It’s also (arguably, of course) the team’s biggest issue ...

The San Francisco 49ers (6-10) are in unfamiliar territory as the 2024 regular season concludes. For the first time since the 2020 season, the 49ers failed to make the playoffs. After winning the ...

After a mostly healthy 2024, San Francisco 49ers quarterback Brock Purdy's season has come to an early end. Head coach Kyle Shanahan announced on Wednesday that Purdy will miss the team's season ...

It's been a disappointing season for both the San Francisco 49ers and Miami Dolphins. Each team came into the year with playoff expectations, but heading into Week 16, both teams have been all but ...

San Francisco 49ers linebacker De’Vondre Campbell stunned the NFL world on Thursday night when it was learned he refused to go into the game against the Los Angeles Rams. Campbell lost his ...