Powerful new applications of what is known as next-generation sequencing are now helping with identification of degraded ...

From the time we are conceived and through old age, genetic mutations accumulate in all our tissues, eluding the body's ...

More than 4,000 years ago, Egypt and Mesopotamia stood as two of the most complex societies on the planet. But the new DNA ...

Plant RNA viruses pose a significant threat to global agriculture, affecting a vast array of crop species and leading to ...

Background: Approximately 3-5% of human cancers are cancer of unknown primary (CUP). Treatment of a cancer patient is largely dependent on the tumor origin. Therefore, identification of the tumor ...

To investigate the effects of DpCs on DNA replication, we have constructed plasmid DNA containing a 10-mer Myc peptide covalently linked to C7 of 7-deaza-dG, a hydrolytically stable mimic of N7-dG ...

In a cell, DNA replication begins at specific locations in the genome, called "origins". Unwinding of DNA at the origin, and synthesis of new strands, forms a replication fork.

There are currently no FDA-approved treatments. To model this disease, the Company's study utilized the Sen57wrn-/-ND6-/+ zebrafish model, which replicates key features of Werner Syndrome, including ...

The model, called ether0, outperforms other advanced AIs at chemistry tasks and is a stepping stone towards automating the entire research pipeline. The model, called ether0, outperforms other ...

DNA is a blueprint of life. Since Watson and Crick proposed its three-dimensional structure, (1) much effort has been spent to understand its structure and dynamics. Formation of the Watson–Crick ...