Semiconservative replication was not the only model of DNA replication proposed during the mid-1950s, however. In fact, two other prominent hypotheses were put also forth: conservative replication ...

During DNA replication, special enzymes move up along the DNA ladder, unzipping the molecule as it moves along. New nucleotides move in to each side of the unzipped ladder. The bases on these ...

This experiment revealed a pattern that supports the semiconservative model of DNA replication. FURTHER RESEARCH: If you continued this experiment for two more generations (as Meselson and Stahl ...

This new study provides definitive evidence about how these secondary DNA structures can pose physical barriers to DNA replication machinery ... provided a working model. "Our study showed ...

empirically derived model of replication fork formation and unwinding, bridging gaps left by previous static or incomplete structural analyses. The study found that LTag helicase unwinds DNA ...

An international research team has provided a detailed insight into how the spatial organization of genetic material is established in the cell nucleus of early embryos within the first hours after ...

This is a model for monitoring and repairing damaged DNA (left figure). The crystal structure of the DNA control protein Rad26 that is responsible for bringing the Rad3 kinase to damaged DNA and ...

The team initially set out to study another replication machinery protein ... “This experiment is really the nail in the coffin of this model where everything is sitting stably on the DNA,” van Oijen ...

Researchers at City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S.

City of Hope researchers demonstrate proof of concept for a novel targeted therapy for pancreatic cancer, exploiting transcription-replication conflicts to combat treatment resistance.