Semiconservative replication was not the only model of DNA replication proposed during the mid-1950s, however. In fact, two other prominent hypotheses were put also forth: conservative replication ...

Saccharin destabilizes bacterial membranes and interferes with DNA replication, causing lysis and impairing virulence traits.

This study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights ...

MSK researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer.

Scientists have provided the most detailed account yet of the earliest stages of DNA replication, an essential process for ...

A team led by Professor Kazuhiro Maeshima of the National Institute of Genetics (ROIS) and SOKENDAI in Japan has developed a ...

During DNA replication, special enzymes move up along the DNA ladder, unzipping the molecule as it moves along. New nucleotides move in to each side of the unzipped ladder. The bases on these ...

The team initially set out to study another replication machinery protein ... “This experiment is really the nail in the coffin of this model where everything is sitting stably on the DNA,” van Oijen ...

This experiment revealed a pattern that supports the semiconservative model of DNA replication. FURTHER RESEARCH: If you continued this experiment for two more generations (as Meselson and Stahl ...

This new study provides definitive evidence about how these secondary DNA structures can pose physical barriers to DNA replication machinery ... provided a working model. "Our study showed ...