Referrals to PR and PC for IPF patients in England remain low, despite evidence of their benefits. Smoking history, COPD diagnosis, and male sex were positively associated with PR referrals.

Comorbidities can obscure IPF symptoms, leading to diagnostic delays or misdiagnoses, complicating the clinical presentation. Comprehensive evaluation is crucial to tailor treatment plans ...

Idiopathic Pulmonary Fibrosis (IPF) is a frightening, incurable disease where the lungs become increasingly damaged by scar tissue, resulting in breathing getting progressively more difficult.

Introduction Oral pirfenidone reduces lung function decline and mortality in patients with idiopathic pulmonary fibrosis (IPF). Systemic exposure can have significant side effects, including nausea, ...

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In turn, CBX7 was involved in the activation of KLF2 target genes, including genes related to endothelial-to-mesenchymal transition (endoMT), WNT9, and TEK. Here, we show that a loss of Cbx7a/CBX7 ...

Endothelial-to-mesenchymal transition (EndoMT) is a transdifferentiation by which endothelial cells (ECs) lose their specific morphology/markers and acquire myofibroblast-like features. Here, we ...

No­var­tis has ter­mi­nat­ed a mid-stage tri­al of an oral treat­ment can­di­date for id­io­path­ic pul­monary fi­bro­sis, the com­pa­ny con­firmed to End­points News.