George Kittle and Charvarius Ward both missed practice Thursday, three days shy of the 49ers’ visit to Los Angeles where they ...

But the way he ran his routes, the way he blocked, he had a hell of a game." Aiyuk will be relied upon more heavily in the coming weeks, with wide receiver Deebo Samuel sidelined due to a calf strain.

The San Francisco 49ers saw the Los Angeles Rams' extensive list of injuries ahead of their Week 3 matchup and upped the ante. 49ers All-Pro tight end George Ki ...

Greg Papa joins "49ers Talk" host Matt Maiocco and discusses if 49ers wide receiver Brandon Aiyuk will step up in Rams ...

Just two games into the season, the Rams (0-2) are approaching desperate times as they prepare to face the San Francisco ...

If Kittle does miss Sunday's game, he will join star running back Christian McCaffrey, who is currently on the Injured ...

Defensive coordinator Nick Sorensen and run game coordinator and offensive line coach Chris Foerster reviewed the 49ers ...

San Francisco 49ers tight end George Kittle may miss Week 3's matchup with the Los Angeles Rams after missing Thursday's ...

The Niners are lost All-Pro running back Christian McCaffrey and star receiver Deebo Samuel to injuries before Kittle ...

San Francisco 49ers tight end George Kittle might miss Week 3's game with a hamstring. View the 49ers TE depth chart inside.

Despite grappling with injuries to key players like Deebo Samuel and Christian McCaffrey, the 49ers are set to demonstrate ...