Sphingolipid - Wikipedia
Sphingolipids are a class of lipids containing a backbone of sphingoid bases, which are a set of aliphatic amino alcohols that includes sphingosine. They were discovered in brain extracts in the 1870s and were named after the mythological sphinx because of their enigmatic nature.
Sphingolipids - Chemistry LibreTexts
Sphingolipids are a second type of lipid found in cell membranes, particularly nerve cells and brain tissues. They do not contain glycerol, but retain the two alcohols with the middle position occupied by an amine.
Sphingolipids and their metabolism in physiology and disease
Nov 22, 2017 · Sphingolipids are a major class of lipids, comprising various species with diverse functions. In addition to being structural elements of membranes, many sphingolipids are bioactive and...
An overview of sphingolipid metabolism: from synthesis to ...
Sphingolipids constitute a class of lipids defined by their eighteen carbon amino-alcohol backbones which are synthesized in the ER from nonsphingolipid precursors.
Sphingolipid - an overview | ScienceDirect Topics
Sphingolipids are a class of lipids characterised by the presence of a sphingosine backbone. This includes a range of lipids including ceramide, sphingosine and sphingomyelin. A range of different cellular functions for sphingolipids have been described. Sphingolipids are a key structural component for membranes, including lipid rafts [57].
Sphingolipid | Membrane Structure, Signaling & Metabolism ...
Sphingolipid, any member of a class of lipids (fat-soluble constituents of living cells) containing the organic aliphatic amino alcohol sphingosine or a substance structurally similar to it. Among the most simple sphingolipids are the ceramides (sphingosine plus a fatty acid), widely distributed in.
Regulation of cellular and systemic sphingolipid homeostasis
Jun 18, 2024 · This Review discusses the regulation of sphingolipid metabolism at the subcellular and organismal levels and explores the therapeutic potential of targeting sphingolipids in human diseases.